Structural Biology

Structure Prediction by Hybrid Approach

Structural Biology Conference focus on Structure Prediction by Hybrid Approach and Sequence Analysis, which involves the topics profile comparison, sequence analysis, gene prediction, protein structure determination. Hydrophobic interactions are a noteworthy power in protein folding and various hydropathy scales have been produced to evaluate the relative hydrophobicity of the amino acids. Hydropathy profiles can be used to examine the surface features of proteins in order to generate hypotheses that can be confirmed experimentally. Sequence analysis can be explained as a process of exposing DNA, RNA or peptide sequence to a wide range of analytical methods in order to understand its structure, function and evolution. The methods include sequence alignment, biological databases. The sequences are being compared to that of the known functions, harmoniously to understand the biology of the organism which gives the new sequence. Synergistic use of three-dimensional structures and deep sequencing is done to realize the effect of personalized medicine.